Compound aminopyrine injection
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Detailed Description
[main ingredients] aminopyrine and barbital
[properties] this product is colorless to light yellow clear liquid.
[pharmacological action]
Pharmacodynamics aminopyrine is a kind of cyclooxygenase inhibitor, which inhibits the conversion of prostaglandin precursor arachidonic acid to prostaglandins by inhibiting the activity of cyclooxygenase, so as to reduce the synthesis of prostaglandins, and then produce antipyretic, analgesic, anti-inflammatory and anti rheumatic effects. Combined with barbiturates can enhance the analgesic effect.
Pharmacokinetics the product is rapidly absorbed after oral administration, mainly metabolized in the liver, demethylated to form 4-aminoantipyrine, and further acetylated to inactive n-acetyl-4-aminoantipyrine; It is not acetylated in horses and mainly produces 4-methylaminoantipyrine. Metabolites are excreted in urine as prototypes or in combination with glucuronic acid and sulfuric acid. The half-life is 1-4 hours.
[function and use] antipyretic analgesics. It is mainly used for antipyretic and anti rheumatism in horses, cattle, sheep, pigs and other animals. It can also be used for colic in equine animals, but the analgesic effect is poor.
[usage and dosage] intramuscular and subcutaneous injection: one dose, 20-50ml for horses and cattle; Sheep and pigs 5-10ml.
[adverse reactions] excessive dose or long-term application may cause methemoglobinemia, hypoxia, cyanosis, neutropenia, etc.
[precautions] continuous and long-term use can cause neutropenia, and the hemogram should be checked regularly.
[drug withdrawal period] 28 days for cattle, sheep and pigs; The milk abandonment period is 7 days.
[Specification] 10ml
[package] 10ml × 10 pieces/box
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